VERATRIC ACID (3,4-DIMETHOXYBENZOIC ACID)

VERATRIC ACID
PRODUCT IDENTIFICATION
CAS NO.	93-07-2
EINECS NO.	202-215-7
FORMULA	(CH₃O)₂C₆H₃COOH
MOL WT.	182.18
H.S. CODE	2918.99.4700
TOXICITY	LD50 ipr-mus >800 mg/kg
SYNONYMS	3,4-Dimethoxybenzoic acid; Veratric acid;
3,4-Dimethylprotocatechuic acid; Acide vératrique; Veratrumsäure; ácido verátrico;
SMILES	c1c(c(ccc1C(O)=O)OC)OC
CLASSIFICATION	Carbocyclic carboxylic acids
EXTRA NOTES
PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL STATE	White to beige crystalline powder
MELTING POINT	179 - 182 C
BOILING POINT
SPECIFIC GRAVITY
SOLUBILITY IN WATER	`partially soluble`
pH
VAPOR DENSITY
AUTOIGNITION
NFPA RATINGS	Health hazard: 2, Flammability: 0, Physical hazards: 0
REFRACTIVE INDEX
FLASH POINT	> 100 C
STABILITY	Stable under ordinary conditions
EXTERNAL LINKS & GENERAL DESCRIPTION
Wikipedia Linking - Benzoic acid Google Scholar Search Drug Information Portal (U.S. National Library of Medicine) - Veratric acid PubChem Compound Summary - Veratric acid http://www.ebi.ac.uk/ - Veratric acid http://www.ncbi.nlm.nih.gov/ - Veratric acid Local: Benzoic acid derivatives substituted by hydroxy group or ether containing oxygen atom have active bacteriostatic and fragrant properties. They are typically used in pharmaceutical and perfumery industry. The destructive metabolic property of oxygen containing benzoic acid derivatives such as protocatechuic acid (3,4-dihydroxybenzoic acid) and veratric acid (3,4-dimethoxybenzoic acid) is used in the application for pharmaceuticals. Veratric acid is a white solid `partially soluble` in water but very soluble in hot water. Its melting point is equal to 181 C. It plays an important role in producing antibiotics and various dyes. Protocatechuic acid is a catabolite of epinephrine. Prazosin, a peripheral vasodilator and antihypertensive, is also an example of the application of veratric acid. Hydroxy and ether substituted benzoic acids feature analogue metabolite of aspirin (acetylsalicylic Acid). They are used as intermediates for pharmaceuticals (especially for antipyetic anlgesic, antirheumatism) and other organic synthesis. They are used as matrix for ionization of peptides, proteins and carbohydrates.
SALES SPECIFICATION
APPEARANCE	White to beige crystalline powder
ASSAY	99.0% min
MOISTURE	0.5% min
MELTING POINT	180 C
TRANSPORTATION
PACKING	50kgs in Fiber Drum
HAZARD CLASS
UN NO.
SAFETY INFORMATION
HAZARD OVERVIEW	Irritant
GHS
SIGNAL WORD	Warning
PICTOGRAMS
HAZARD STATEMENTS	H315-H319-H335
P STATEMENTS	P261-P305 + P351 + P338
EC DIRECTIVES
HAZARD CODES
RISK PHRASES	36/37/38
SAFETY PHRASES	26-36
PRICE INFORMATION